15 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... splenomegaly, abnormal neurology ... , back pain Haematology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... pulses, bruits, or blood ... asymmetric arm BP readings ... affects the skin, neurologic ... cognitive impairment, neurologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... inflammation, leading ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS #neurology ... #management #treatment
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... Causes purpura & ... Borrellia (Lyme disease ... #Transfusion #diagnosis ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... easy bruising to purpura ... (Petechial or purpuric ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Post Transfusion Purpura ... Causes purpura & ... Borrellia (Lyme disease ... #Transfusions #diagnosis ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... Cutaneous: palpable purpura ... reveals increasing blood ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... • Severe Liver Disease ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
Marfans, EDS ... • Aortic valve disease ... ~60 • Control blood ... Aortic #Dissection #diagnosis ... #management #vascular
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... on bone marrow leading ... extramedullary disease ... #Leukemia #Hematology ... #Oncology #Diagnosis