11 results
Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
women in the child-bearing ... central dot. - LIP ... #Clinical #Diagnosis ... #Radiology #CTChest ... #Differential #Comparison
Low Attenuation pattern 
1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of
(LAM): uniform cysts ... woman of child-bearing ... #Clinical #Radiology ... #HRCT #CTChest ... #Pattern #Comparison
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
(LAM): regular cysts ... woman of child-bearing ... #Clinical #Radiology ... #HRCT #CTChest ... #Pattern #Comparison
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
(LAM, LIP, Langerhans ... pattern can be readily ... on the basis of HRCT ... LowAttenuation #Differential ... #Diagram #Comparison
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... pattern we are dealing ... The cystic pattern ... in many cases UIP ... #Diagnosis #Radiology
Cavities frequently arise within a mass or an area of consolidation as a result of necrosis.
We
In the differential ... can heal and end up ... #Clinical #Diagnosis ... #Radiology #CTChest ... Emphysema #Comparison
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
cut-offs defined in clinical ... BAL GM does not differentiate ... Positives: - Pip ... Fungal #Biomarkers #BetaDGlucan ... Galactomannan #diagnosis #comparison
UIP with honeycombing (left) and chronic HP (right)
Differential diagnosis of Hypersensitivity Pneumonitis.
Subacute stage:
- RB-ILD: seen in
chronic HP (right) Differential ... show very similar HRCT ... #Clinical #Diagnosis ... #Radiology #CTChest ... #UIP #Comparison
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
formulations (eg ... in BAL does not differentiate ... False positives: Pip ... 100d following HCT ... blood products #BetaDGlucan
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Clinical • Under-recognized ... Period • Breast-feeding ... support for patients clinically ... diagnosis #management #cardiology