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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round

Cystic LCH: - LAM ... Centrilobular emphysema ... central dot. - LIP #Clinical ... #Comparison #Table ... #RadiologyAssistant

Low Attenuation pattern
1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of

Lymphangiomyomatosis (LAM ... Centrilobular emphysema ... #Clinical #Radiology ... #Pattern #Comparison ... #Table #RadiologyAssistant

Low Attenuation pattern (2)
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery

Centrilobular emphysema ... Lymphangiomyomatosis (LAM ... #Clinical #Radiology ... #Pattern #Comparison ... #Table #RadiologyAssistant

The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-

- Lung cysts (LAM ... pattern can be readily ... #Diagnosis #Radiology ... Differential #Diagram #Comparison ... #RadiologyAssistant

On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans

#Clinical #Diagnosis ... #Radiology #CTChest ... #Cystic #Comparison ... #LAM #LIP #Histiocytosis ... #RadiologyAssistant

There is a hydropneumothorax.
Notice the air-fluid level (blue arrow).
The upper lobe is still attached to the

There is a lung cyst ... small airways leading ... to pulmonary cyst ... #Clinical #Radiology ... #RadiologyAssistant

Cavities frequently arise within a mass or an area of consolidation as a result of necrosis.
We

associated pulmonary emphysema ... #Clinical #Diagnosis ... #Radiology #CTChest ... Emphysema #Comparison ... #RadiologyAssistant

Differential diagnosis of Lymphangiomyomatosis:
Langerhans cell histiocytosis: > 90% are smokers, cysts have irregular shapes and the

90% are smokers, cysts ... Centrilobular emphysema ... typical case of LAM ... #Clinical #Radiology ... #Cystic #RadiologyAssistant

Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient

before the typical cysts ... #Clinical #Radiology ... Nodular #Pattern #Comparison ... #Table #RadiologyAssistant

On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary

before the typical cysts ... #Clinical #Diagnosis ... #Radiology #Pulmonary ... #Differential #Comparison ... #Table #RadiologyAssistant

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