13 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology #Mechanisms #DOAC ... #Hematology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Rivaroxaban #Edoxaban #Loading ... #DVT #Pharmacology ... #Hematology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
: Prevention of ... decompensation, Prevention ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology ... #indications #dosing
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Preventing Decompensation in Cirrhosis 

cACLD, CSPH, and the Rule of Five
Prevention of Decompensation
Nonselective Beta Blockers (NSBB)
Preventing
Preventing Decompensation ... Rule of Five Prevention ... Blockers (NSBB) Preventing ... #treatment #management ... #hepatology #gastroenterology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
Antivirals #table #treatment ... #hcv #medications ... infectiousdisease #hepatology ... HepatitisC #Management #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... management #algorithm #pharmacology ... #treatment #medications ... decisionaid #cardiology #hematology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Gastroenteritis: Treatment ... consultation for non-healing ... Concern for HES: • Hematology ... Gastroenteritis #Treatment ... #management #gastroenterology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
nutrients • TPN for treatment ... excluded limb • Treatment ... and prevention ... and Hepatology ... gastric #bypass #gastroenterology