15 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #Dosing #Oral #Anticoagulant ... Rivaroxaban #Edoxaban #Loading ... #DVT #Pharmacology ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Pathway - Aspirin, anticoagulants ... APS), Secondary prevention ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Sensorineural hearing ... Anticoagulants ... arterioles - Treatment ... David #Susac #Syndrome
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Topical steroids • Prevention ... Behcets #disease #Syndrome ... #pharmacology # ... rheumatology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
procedure Stop anticoagulant ... treatment; volume ... Reversal #NOAC #Oral #anticoagulant ... #hematology #management ... #pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... IL-1 and IL-6, leading ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
Consider refeeding syndrome ... nutrients • TPN for treatment ... deficiencies) Dumping Syndrome ... and prevention ... Gastroenterology and Hepatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
capillary leak syndrome ... et diutinum Neurologic ... Hyperviscosity syndrome ... cold IgG • Lupus anticoagulant ... Paraproteinemias #Hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
emphasis placed on prevention ... causing hypovolemia needing ... acute coronary syndrome ... then placed on prevention ... icu #clinical #pharmacology