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The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Primary Syphilis ... Secondary Syphilis ... and secondary syphilis ... or secondary syphilis ... #Primary #Secondary
Mucous patches in Secondary Syphilis

Mucous patches form during the breakdown of mucous membranes, seen here on
Secondary Syphilis ... stage of syphilis ... mouth, vulva, and ... #Secondary #Syphilis ... Tongue #Clinical #Photo
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis ... of secondary syphilis ... fever (50-80%) ▪ Mucous ... the palms of the hands ... Diagnosis #Clinical #Photo
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Stages of Syphilis ... Early Primary: ... lymphadenopathy Early Secondary ... include palms and ... Condyloma lata • Mucous
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Treatment 1) Primary ... Genitalia, oropharynx, rectum ... treatment. 2) Secondary ... ulcerated • MSK ... , secondary and
Primary Syphilis
Usually, a single ulcer (chancre) appears at the site where the bacteria entered the body.
Primary Syphilis ... syphilis usually ... progresses to the secondary ... #Primary #Syphilis ... Diagnosis #Clinical #Photo
Primary syphilis on penile shaft

Primary lesion appears after an incubation of 2-6 weeks
Single painless papule that
Primary syphilis ... becomes eroded and ... contact: penis, rectum ... firm #Clinical #Photo ... #Syphilis
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Amyloidosis: • Primary ... dyscrasias • Secondary ... Hepatomegaly: Bruising • Primary ... salivary glands, or rectal ... mucosa) • Congo
Ulcerative Proctitis
Proctitis:
 • Affects 1/3 patients
 • Predictors of extension:
     - Disease
Topical therapy primary ... despite PO steroids and ... to the inflamed mucosa ... c-Diff, GCCT (LGV), syphilis ... Alternative Dx: IBS, rectal