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diagnosis differential hematology abnormal bruising intravascular prolonged pt algorithm anemia avnrt bleeding cardiology disseminated extravascular hemolysis hemolytic hemorrhage hemostasis management
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... intravascular coagulation ... (DIC) c. ... #Prolonged #Causes
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
(DIC) Overview ... • Prolonged PT/PTT ... Treat primary cause ... INR < 2.3 - APTT ... #diagnosis #causes
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... Causes include : ... intravascularcoagulation (DIC ... differential #hematology #coagulation
Visual Guide to AV Nodal Reentrant Tachycardia (AVNRT) - Pathophysiology - Dual AV nodal physiology is
Visual Guide to AV ... Nodal Reentrant ... Pathophysiology - Dual AV ... - In most case ... ECG usually shows
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Uterine fatigue (e.g ... intravascular coagulation ... (DIC) • Anti-coagulation ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... (DIC) - HELLP ... (usually IgG) (e.g ... Extravascular #Causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... Warfarin • Acute DIC ... intravascular coagulation ... discern these causes ... disease • Acute DIC
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... intravascular coagulation ... infiltration (e.g ... Purpura #Bruising #Causes
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