8 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTT, Normal PT ... PTT, Normal PT ... Differential #Diagnosis ... #Hematology #coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... PT and aPTT 1. ... (DIC) c. ... #aPTT #Prolonged ... #differential #
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... aPTT are both prolonged ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... INR < 2.3 - APTT ... #diagnosis #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... intravascular coagulation ... (DIC) - HELLP ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... prolonged after ... discern these causes ... disease • Acute DIC
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... - History of bleeding ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... changes), high MCV anemia
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... intravascular coagulation ... Purpura #Bruising #Causes ... pediatrics #diagnosis #differential