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diagnosis differential anemia coagulation hemolytic abnormal algorithm aptt bleeding bruising disseminated hemolysis hemorrhage hemostasis management obgyn obstetrics postpartum pph pt
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - Intravascular ... vs Extravascular ... Causes Intravascular ... coagulation (DIC ... #Extravascular
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Disseminated intravascular ... coagulation (DIC ... #differential #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... IVIG infusion Intravascular ... : TTP, HUS, DIC, ... #classification ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... Treat primary cause ... #Disseminated #Intravascular ... treatment #management #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... . prolonged/induced ... • Disseminated intravascular ... coagulation (DIC ... Diagnosis #Algorithm #Causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
the PT remains prolonged ... , disseminated intravascular ... discern these causes ... disease • Acute DIC ... Differential #Diagnosis #Hematology
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