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diagnosis differential coagulation abnormal disseminated management treatment algorithm anemia bleeding bruising hemolysis hemolytic hemophilia hemorrhage hemostasis isth laboratory obgyn obstetrics
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - Intravascular ... vs Extravascular ... Causes Intravascular ... coagulation (DIC ... #Extravascular
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... PT and aPTT 1. ... Disseminated intravascular ... coagulation (DIC ... #aPTT #Prolonged
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... aPTT are both prolonged ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... PT/PTT • Low ... INR < 2.3 - APTT ... #Disseminated #Intravascular
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
for Disseminated Intravascular ... Coagulation (DIC ... , aPTT: • Expected ... #Disseminated #Intravascular ... Scoring #diagnosis #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
prolonged after ... , disseminated intravascular ... discern these causes ... disease • Acute DIC ... Differential #Diagnosis #Hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... . prolonged/induced ... • Disseminated intravascular ... coagulation (DIC ... Diagnosis #Algorithm #Causes
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
is prolonged, but ... normal in mild cases ... ) • PT/INR & von ... hemophilia type (e.g ... Management #treatment #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
be performed PT ... , PTT, and fibrinogen ... decrease in most cases ... reflection of intravascular ... Diagnosis #Workup #Hematology
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