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differential coagulation abnormal aptt bruising thrombocytopenia algorithm anemia atlas basics blanching bleeding bruise dermatology disseminated ecchymosis hematomas hemolysis hemolytic hemorrhage
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... - Disseminated intravascular ... coagulation (DIC ... thrombocytopenic purpura ... #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... coagulation (DIC ... #Causes #diagnosis ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... #Disseminated #Intravascular ... #Coagulation #diagnosis ... #management #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... - Differential Diagnosis ... . prolonged/induced ... • Disseminated intravascular ... coagulation (DIC
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged ... intravascularcoagulation (DIC ... #Causes #diagnosis ... #differential #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... - DIC (disseminated ... intravascular coagulation ... #Bruising #Causes ... peds #pediatrics #diagnosis
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
ecchymosis) is caused ... of blood in the extravascular ... Excessive bruising & prolonged ... to be normal, PT ... Diagnosis VWF
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... prolonged after ... , disseminated intravascular ... discern these causes ... #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... activity is the diagnostic ... be performed PT ... reflection of intravascular ... #Workup #Hematology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... PETECHIAE and PURPURA ... flat macules of extravascular ... Purpura are larger ... nettle sting #Diagnosis
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