31 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Diagnosis and Management ... than 1500 and clinical ... #diagnosis #hematology ... #differential #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... lesions • Derm referral ... • Early ophtho referral ... #Treatment #management ... #pharmacology #rheumatology
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Pathogenesis and Clinical ... Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... Bilateral, asymmetric corneal ... pathophysiology #ophthalmology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... Amyloidosis • Chorea ... Amyloidosis • Eosinophilic ... differential #diagnosis #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... 95% of cases (Cornelia ... them, but urgent rheumatology ... required +/- prompt ophthalmology ... Symptoms #Diagnosis #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... inhibitors • Uveitis- Ophthalmology ... #diagnosis #management ... signs #symptoms #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... - Hepatitis, eosinophilic ... Anemia #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Clinical Presentation ... Fever is the main clinical ... #Diagnosis #Management ... #Hematology #Rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... cardiomyopathy, Horner ... #diagnosis #management