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management diagnosis hematology hemophagocytic lymphohistiocytosis rheumatology algorithm latenttb neurology syndrome tb tuberculosis 5asa acromegaly als amyotrophic behcet calcium classification colitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... diagnosis #management #treatment
Persistent UC Symptoms Despite 5-ASA Therapies • Assess for Drug Adherence • Disease Activity Assessment (bloody
Drug Adherence • Disease ... Activity Assessment ... diarrhea correlates w active ... Escalate Treatment ... Persistent #5ASA #Refractory
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... age, however the disease ... absent NK cell activity ... • Bicytopenia Treatment ... diagnosis #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... or autoimmune disease ... , treatment of underlying ... transplantation for refractory ... disease - Dr.
Esophageal Crohn's Disease Management Algorithm Assess for Active Symptoms and for Stricturing/Fistulizing Disease Stricturing DX: • Bx r/o
Esophageal Crohn's Disease ... Algorithm Assess for Active ... Stricturing/Fistulizing Disease ... Mitomycin C • Refractory ... Management #Algorithm #treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Syndrome Systemic disease ... common in Asia • HLA-B51 ... Inflammatory eye disease ... Arthritis, AS Treatment ... azathioprine • Severe or refractory
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... rich classical HL ... • PET scan - activity ... number of sites of disease ... Hodgkin Lymphoma Treatment
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... adenoma, ↓(TFT, LH ... Radiotherapy: Relapse or refractory ... Endocrinology #Treatment ... #Pathophysiology
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