18 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Dermatomyositis Erythema chronicum ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... hemolysis, deficiency anemia ... • Infections: Chronic ... #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Demyelinating syndromes ... (75%): Anemia ( ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... = RA, SLE, psoriatic ... #rheumatology # ... approach #workup #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... : • Symptoms limited ... : • Chronic B-cell ... #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... : Chronic disease ... #table #rheumatology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blasts with a relatively ... bone pain, fever, joint ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... • A clinical diagnosis ... #Rheumatology # ... diagnosis #management ... #Dermatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... sensitize red blood ... #hematology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... • Improve the symptoms ... result from low blood ... #oncology #hematology ... #diagnosis #management