15 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... pain • loss of secondary ... , ↓ALPLow ... : - respiratory ... • Elevation of
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis ... Weakness, fatigue, nausea ... insufficiency • Low ... baseline ACTH - Secondary ... Diagnosis #Algorithm #endocrinology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... , High R - Secondary ... Al, Low R - Pseudo-hyperaldosteronism ... Syndrome, Congenital Adrenal ... Algorithm #nephrology #causes
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... • Starvation Secondary ... Lymphoblastic Leukemia (ALL ... Diagnosis #Algorithm #endocrinology ... #causes
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
specificity for AI (but low ... excludes AI in almost all ... Step 3) Differentiate ... - Low ACTH is ... #Stimulation #Endocrinology
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
weakness (defined as low ... pressure or low ... Phosphate is a cause ... , condition of renal ... pathophysiology #pulmonary
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... Methotrexate ILD Secondary ... pneumonia (COP), Respiratory ... ILD #diagnosis #differential ... #pulmonary #causes
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
Causes of ST Segment ... Elevation - Differential ... - Coving ST Secondary ... QRS complex Pulmonary ... Tower sign) and low-amplitude
Causes of Hypocalcemia by Clinical Cause

Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
severe illness - Secondary ... Neck surgery - Low ... gland removal Renal ... #Differential # ... Diagnosis #Endocrinology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... Acidosis - Differential ... LV failure - Low ... output - Acute pulmonary ... #Differential #