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diagnosis systemic differential autoimmune erythematosus lupus myositis scleroderma sclerosis sle vasculitis antinxp2 antinxp2dm arthritis classification dermatology management myopathy ra rheumatoid
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
• Scleroderma renal ... Scleroderma #diagnosis #signs ... #symptoms #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... Dermatomyositis ... heliotrope rash, Shaw sign ... , holster sign, ... Myositis #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... : scleroderma renal ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Abdominal pain (20%) Renal ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Pericarditis • Renal ... Arthritis #RA #Signs ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... Presentation - Systemic Symptoms ... purpura: strong sign ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Anti-NXP-2 Dermatomyositis ... chest (in a V-sign ... shoulders (in a shawl sign ... • Clear cell renal ... diagnosis #management #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... symptoms • Anti-CADM ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology
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