7 results
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Rhabdomyolysis • Renal ... failure • Metabolic ... acidosis • ARDS ... Colchicine #Toxicity #Toxicology ... #Symptoms #Signs
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
and biochemical signs ... • Metabolic acidosis ... Hyperkalemia and renal ... failure By Dr ... #Pharmacology #
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
and metabolic acidosis ... gap metabolic acidosis ... coagulopathy, renal ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... all • Heart Failure ... • Discuss with endocrinology ... considerations: Addison's, Renal ... Tubular Acidosis
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
- Multi-organ failure ... Metabolic: Metabolic acidosis ... hyperglycemia Other: Renal ... Colchicine #Toxicity #Toxicology ... #Phases #Pharmacology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
leads to Metabolic Acidosis ... Metabolic Acidosis ... failure possibly ... #criticalcare #management ... diagnosis #treatment #pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
syndrome (PRIS) - acidosis ... , bradycardia. renal ... /liver failure, ... No pharmacologic ... CriticalCare #diagnosis #management