26 results
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Colchicine Toxicity ... Rhabdomyolysis • Renal ... failure • Metabolic ... acidosis • ARDS ... Toxicology #Symptoms #Signs
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
Gap Metabolic Acidosis ... Aspirin - salicylate toxicity ... ketoacidosis Renal ... acids in advanced renal ... failure Ketoacidosis
Hyperkalemia - Differential Diagnosis - Impaired Excretion vs Redistribution

Impaired Urinary Excretion 
 - Renal failure
 -
Excretion - Renal ... failure - Hypoaldosteronism ... Succinylcholine - Digoxin toxicity ... deficiency - Acidosis
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
and metabolic acidosis ... gap metabolic acidosis ... coagulopathy, renal ... failure) Hepatotoxicity ... Toxicology #Diagnosis #Management
Proximal Renal Tubular Acidosis (RTA) Ttype 2 Overview

HCO3 reabsorptive failure
Lowering of threshold for HCO3 absorption in
Proximal Renal Tubular ... Acidosis (RTA) ... HCO3 reabsorptive failure ... #RenalTubular #Acidosis ... Proximal #Diagnosis #Management
Hyperkalemic Distal Renal Tubular Acidosis (RTA) Type 4 - 

Failure to acidify urine in collecting duct
Hyperkalemic Distal Renal ... Tubular Acidosis ... ) Type 4 - Failure ... Hyperkalemic #Diagnosis #Management ... #RenalTubular #Acidosis
Distal Renal Tubular Acidosis (RTA)  Type 1 

Totally scuppers the kidney's acidification mechanism. Will be
Distal Renal Tubular ... Acidosis (RTA) ... What is it Failure ... Distal #Diagnosis #Management ... #RenalTubular #Acidosis
Toluene Poisoning - Diagnosis and Management Summary
What is it?  Volatile hydrocarbon, Glue or paint-sniffing, Occupational
Diagnosis and Management ... lipid-soluble, Toxicity ... effects (inc psych) Renal ... Early raised AG acidosis ... , ↓K+ Renal - chronic
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
and biochemical signs ... • Metabolic acidosis ... Hyperkalemia and renal ... failure By Dr ... #Pharmacology #Toxicity
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
• Diabetic acidosis ... - Renal ... • Chronic renal ... failure • ... Diagnosis #Algorithm #endocrinology