311 results
The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth
Cyclin-dependent kinases (CDKs ... factor (regulators) Retinoblastoma ... Cyclin-dependent kinase #CDK ... transcription factor #Rb #Retinoblastoma
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma: ... Unilateral Somatic Retinoblastoma ... Bilateral Germline Retinoblastoma ... Strabismus #Retinoblastoma
Assessing and referring childhood cancers #Diagnosis #PrimaryCare #Peds #ChildhoodCancers #ClinicalFeatures #Lymphoma #Wilms #Leukemia #Retinoblastoma #BMJ
Wilms #Leukemia #Retinoblastoma
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
- Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... Rarely can be CD4
Leukocoria on Ocular Examination

#Leukocoria #Ocular #PhysicalExam #clinical #video #ophthalmology #retinoblastoma #pediatrics
ophthalmology #retinoblastoma
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Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- T-cell - CD7 ... , CD3 Chronic ... - B-cell CD5
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
Wilm tumour - Retinoblastoma
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Hx of AKI/CKD ... US w/ PVR - CPK ... 21% - AKI on CKD
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
CD3-CD4+ T cells
HIV Associated Infections Based on CD4 Count 

#Diagnosis #InfectiousDisease #CD4Count #HIV #AIDS #Opportunistic #Infections #OI #Table
Infections Based on CD4 ... #Prophylaxis #CD4