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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
disorders #leukemia #hematology ... #oncology #diagnosis ... #CML #CLL #AML
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... ) CLL Symptoms: ... mosquito bites CLL ... #Leukemia #Hematology ... #Oncology #Diagnosis
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... Hypercalcemia #Anemia
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
• Lymphoid (ALL ... CD10 - T-cell ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... Blood #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... • Neutropenia, anemia ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... Consider stem cell ... (transfusions, antibiotics ... management #treatment #hematology
Autoimmune Hemolytic Anemia (AIHA)

WARM AHA
- Primary - Idiopathics
- Secondary
Infectious
 • Viral- HIV, EBV, HCV, HEV
 •
Autoimmune Hemolytic Anemia ... Lymphoproliferative • CLL ... Drug Exposure • Antibiotics ... Lymphoproliferative • CLL ... Autoimmune #Hemolytic #Anemia
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Increased red cell ... Increased red cell ... breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... Causes #Workup #Hematology
Medications for the Management of Anemia

TREATMENT OF ANEMIA
 - Cyanocobalamin/B12
 - Erythropoietin/epoetin alfa
 - Darbepoetin alfa
Management of Anemia ... TREATMENT OF ANEMIA ... TREATMENT OF SICKLE CELL ... ANEMIA - Hydroxyurea ... Medications #Management #Pharmacology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... ) (e.g. lupus, CLL ... Drugs (Beta lactam antibiotics ... differential #diagnosis #hematology ... #anemia