96 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... twitter.com/AmyChung #AntiCoagulation ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Breakthrough DVT During Anticoagulation ... Subtherapeutic Anticoagulation ... - Behcet's disease ... - May-Thurner syndrome ... #hematology #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Raynaud's Phenomenon on Physical Exam

#Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology
#Raynauds #Syndrome ... #disease #phenomenon ... #clinical #video ... fingers #hands #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
parvovirus B19 infection ... • Lyme disease ... migrans • Lyme disease ... Antiphospholipid-antibody syndrome ... differential #diagnosis #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... for refractory disease ... immunosuppressive meds • +/- Anticoagulation ... #Syndrome #Treatment ... #pharmacology #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
SLE) - Viral infections ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... and Autoimmune Diseases ... deficiency Infections ... Differential #Diagnosis #Hematology
Medial Approach Knee Intra-articular Corticosteroid Injection 

Landmark 1/3 to 1/2 way from top of patella. Find
Corticosteroid Injection ... Corticosteroid #Injection ... #clinical #video ... physicalexam #procedure #msk ... orthopedics #sports #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... cold agglutin disease ... e.g. sickle cell disease ... differential #diagnosis #hematology