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diagnosis differential algorithm lymphadenopathy diffuse focal localized monoclonal acronym classification emergencies extravascular gammopathies hemeonc hemolysis hemolytic hodgkins intravascular leukemia management
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Neoplastic (Leukemia, Lymphoma ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... Lymphadenopathy #LAD ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... •TB • Lymphoma ... Forearm/Hand) • Lymphoma ... Lymphadenopathy #LAD ... #Hematology #Oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... e.g. lupus, CLL, lymphoma ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... (90-95% of cases ... classification #hematology ... #oncology #management
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Renal disease - Cr ... 40 ml/min A - Anemia ... Causes of false- ... MGUS #diagnosis #hematology ... #oncology
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic for Causes ... L - Leukemia, Lymphoma ... A - Aplastic Anemia ... Liver Disease, Lab ... Differential #Diagnosis #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... manifestations, hypoxia, CXR ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... compounds, alcohol, lead ... Syndromes #diagnosis #hematology ... #oncology
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