6 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... with coagulation defects ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... . 1) HELLP (Hemolysis ... #AFLP #Obstetrics ... #OBGyn #Hematology ... Diagnosis #Comparison #Table
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... #comparison #table ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... Consider RBC membrane disorder ... Algorithm #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... Intrinsic RBC Defects ... Extravascular #Causes #differential
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
organ injury: thrombocytopenia ... or severe RUQ pain ... preeclampsia patients • HELLP ... hypertension #htn #obstetrics ... #cardiology #differential