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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis ... #causes
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... - Differential ... Pneumonitis • Treatment ... BrighamChiefs #ILD #Causes ... #Differential #
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... Diagnosis Table ... Cold Agglutinin Disease ... #Diagnosis #Table ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... disorders • Celiac disease ... effect following treatment ... #Hematology
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
hypereosinophilia (HE) Caused ... cytokines Common causes ... Rare causes: ... hypereosinophilia #HE #Differential ... #Diagnosis #Causes
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... - Differential ... Spleen #Enlarged #Differential ... Diagnosis #Algorithm #Causes ... #Hematology
Clues to Differential Diagnosis of Central Cyanosis: Onset of cyanosis, Clubbing, Secondary erythrocytosis, Auscultation, X-ray, Echocardiography,
Clues to Differential ... - Pulmonary diseases ... #Cyanosis #Differential ... Central #Cardiology #Causes ... #Table #Comparison
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
Connective tissue disease-associated ... interstitial lung diseases ... CTILD #Diagnosis #Differential ... #Comparison #Table ... #Pulmonary #Rheumatology
Headache Differential - Primary vs Secondary
A vast number of diseases can cause a headache. We divide
Headache Differential ... vast number of diseases ... can cause a headache ... headaches are caused ... Primary #Secondary #Table
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Non-infectious (malignancy, rheumatologic ... Thrombocytosis #Differential ... #Diagnosis #causes ... #Platelets #hematology