14 results
diagnosis management sle hematology pharmacology classification differential erythematosus hydroxychloroquine oncology systemic vasculitis activation adverseeffects algorithm anemia aplastic benefits chronic cll
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... 200ng/mL Best indications ... Measurement #SLE #rheumatology ... #pharmacology #levels ... #lupus #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Lupusreference #druginduced ... #table #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... recommended with other medications ... Hydroxychloroquine #hcq ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... infections (HAV, HBV, HCV ... hepatitis #DILI #DrugInduced
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... antibodies, Complement levels ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... for 1 year of treatment ... Lupusreference #DrugInduced ... Erythematosus #medications ... differential #diagnosis #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Antithyroid medications ... - CMV - HCV ... index < 2 • EPO Level ... aplastic anemia Treatment ... Anemia #oncology #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Infections: HCV ... rheumatoid factor level ... C4 complement level ... (e.g. systemic lupus ... classification #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
) B symptoms → fevers ... transformation) Treatment ... low-risk disease • Indications ... for Treatment: ... Leukemia #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... Complement (Low levels ... • HIV • HBV HCV ... differential #diagnosis #rheumatology
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