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diagnosis allergy comparison leukemia lymphoma management rheumatology workup algorithm apml causes classification defects dermatologic differentiation diffuse erythematosus gpa granulomatosis immunology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... identical to the non-Hodgkin ... Intussusception, SIB ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... Reed Sternberg cell ... based on: - Cell ... type (B cell, T ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ) CLL Symptoms: ... mosquito bites CLL ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Age > 50 • Chronic ... Reed-Sternberg Cells ... Biopsy • Hodgkin's ... Algorithm #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
cells. ... accounts for 10% of all ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... Marrow Failure • Chronic ... blood count with differential ... #diagnosis #hematology ... #oncology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... structure and cell ... Grey Platelet Syndrome ... comparison #table #differential ... #diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
reticularis Differential ... • Goodpasture syndrome ... • Giant cell arteritis ... disease • Non-Hodgkin ... Polyangiitis #GPA #dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... 2nd pass = Chronic ... Causes: • Mast cell ... activation syndrome ... #Diagnosis #hematology
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