10 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
and biological evidences ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Probiotics Guidelines
Adults with C difficile infection
 • Recommendation: Only in the context of a clinical trial
the context of a clinical ... on antibiotic treatment ... the context of a clinical ... recommendations #management ... #evidence #ebm
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- HIV, CMV, EBV ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... Syndrome #diagnosis #management ... #treatment #neurology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... supraclavicular node • Anterior ... Hodgkin Lymphoma Treatment ... hematology #oncology #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... GrepMed Handbook Clinical ... Acute Diarrhea (>3 BM ... Bezlotoxumab 10 mg/kg ... IDSA 2021 CDI Treatment
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM ... Improve #Outcomes #Evidence
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... spinal MRI • No evidence ... Brucellosis - Dengue, EBV ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... ., EBV) ▪ Malignancies ... Clinical Presentation ... Treatment Approach
Thiopurines in IBD
Indications:
 • Steroid-sparing agents indicated for maintenance of remission in UC and CD
 •
associated to good clinical ... EBV seroconversion ... adults already EBV ... #BowelDisease #Management ... #Treatment
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
populations) CLINICAL ... Birbeck granules (EM ... TREATMENT OPTIONS ... with appropriate treatment ... Histiocytosis #Diagnosis #Management