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oncology differential hemophagocytic hlh lymphohistiocytosis rheumatology treatment anemia aplastic atopic atopy cd4 dermatitis dermatology disorders eczema hemeonc hodgkins icl idiopathic
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU ... #management #treatment
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
symptoms, unexplained hematologic ... and classification ... to 50% of PTLD cases ... Disorders #oncology #diagnosis ... #management #transplant
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Parvovirus B19 - EBV ... Anemia #oncology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... supraclavicular node • Anterior ... ) Classification ... #hematology #oncology ... #management
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Lymphocytopenia DIAGNOSTIC ... CRITERIA FOR ICL ... EBV. CMV. ... #diagnosis #hematology ... #Differential #Causes
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... #management #medications ... #treatment #diagnosis ... #causes #atopy ... Petersen EBM, Skov
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... #rheumatology # ... classification
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... Infections (e.g., EBV ... Approach • Initial management ... #Management #Hematology
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