39 results
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Multiple Uses for ... Thinking MTP YES ICH ... #Indications #management ... #EBM #trauma
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... #management #treatment
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
ejection fraction, treatment ... cardiovascular causes ... hospitalization for the management ... dCHF #Cardiology #EBM
Anterior Shoulder Dislocation - ED Management
The shoulder is the most commonly dislocated major joint, 95% of
Dislocation - ED Management ... ) • ED Management ... MH/CCF/CWRU EM ... Radiology #XRay #Diagnosis ... #Management #Orthopedics
Lung Ultrasound for Diagnosing Pneumonia - Scan through 6 zones (3 per side) 1. Midclavicular line
Ultrasound for Diagnosing ... Midclavicular line on the anterior ... the diaphragm #Diagnosis ... #Peds #EM #PICU
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome - Causes ... and Treatment ... - MH/CCF/CWRU EM ... #Differential #Diagnosis ... #Treatment #Management
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... Subacute to Chronic Causes ... #differential #diagnosis
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
liver>kidney), EBV ... extralymphatic tissues Diagnosis ... to 50% of PTLD cases ... Disorders #oncology #diagnosis ... #management #transplant
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... aplastic anemia Treatment ... oncology #hematology #diagnosis ... #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... Coxsackie, CMV, EBV ... Stills #Disease #diagnosis ... #management #treatment