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Shotgun Laboratory Testing for Severe Acute Livery Injury

https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known

#TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Testing for Severe Acute ... Livery Injury ... #LiverInjury #Diagnosis ... #Workup #Hepatology ... #EBM #ChoosingWisely
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... C, A, E, B, D, EBV ... #Injury #Differential ... #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 20x normal - Acute ... normal - Infection (EBV ... #Injury #hepatology ... transaminitis #differential ... #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... HBV, HCV, HEV, EBV ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... HBV, HCV, HEV, EBV ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... Illness Myopathy (ICU ... renal injury, Strenuous ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis
Distal Radius Fracture 
Distal radius fracture is the most common orthopedic injury. Here's a quick summary.
•
, acute carpal tunnel ... ) • ED Management ... MH/CCF/CWRU EM ... Colles #Distal #Radiology ... #XRay #Diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
HIV, HBV, EBV, ... Sarcoidosis) • Liver ... inflammation (acute ... Gap #ProteinGap #differential ... #diagnosis #hematology