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differential transaminitis algorithm lfts causes aclf chemistry choosingwisely chronic cirrhosis druginduced ebm effusions elevated failure function gap gastroenterology globulin hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... HBV, HCV, HEV, EBV ... dechallenge • Acute ... #Liver #Injury ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Hepatopathy • Acute ... Viral Hepatitis ... (>1000): • DILI ... injury) • Ischemic ... #hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... HBV, HCV, HEV, EBV ... • Iatrogenic: DILI ... #injury #hepatitis ... #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... normal - Infection (EBV ... #Injury #hepatology ... #differential #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... C, A, E, B, D, EBV ... #Diagnosis #Causes ... #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
- Differential Diagnosis ... HAV, HCV, HEV, EBV ... Trauma: Shock liver ... • Iatrogenic: DILI ... #causes #hepatology
Shotgun Laboratory Testing for Severe Acute Livery Injury https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known #TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Testing for Severe Acute ... Livery Injury ... #LiverInjury #Diagnosis ... #Workup #Hepatology ... #EBM #ChoosingWisely
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 Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... Infections: Hepatitis ... A/B/C/D/E, EBV, ... #Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... #chemistry #diagnosis ... #differential #Hepatology
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