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diagnosis treatment hemophagocytic hlh hodgkins lymphohistiocytosis lymphoma oncology rheumatology 1 adultonset cdi cdiff classification clostridioides clostridium comparison difficile disease gastroenterology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
., HIV), EBV infection ... Autoimmune diseases • Clinical ... Etiology: - Infections ... involvement Differential ... #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV ... Disease #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody, Anti-GBM ... Other tests: • CT ... confirm DAH, r/o infection ... seen on chest CT ... #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Diagnosis and Management ... GrepMed Handbook Clinical ... Acute Diarrhea (>3 BM ... equivocal • CT ... Bezlotoxumab 10 mg/kg
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Serologic and EMG ... Imaging - CT Chest ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... infection • Family ... Hodgkin Lymphoma - Clinical ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Triggers: ▪ Infections ... (e.g., EBV) ... Clinical Presentation ... underlying trigger: Infections ... #Hematology #HemeOnc
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