12 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Serologic and EMG ... Bedside: ice pack ... diagnosis #management #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... - Differential ... Infectious: Influenza, EBV ... NMJ disorder (Myasthenia ... Diagnosis #causes #neurology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... , HIV), clostridial ... immobility • Critical ... Illness Myopathy (ICU ... #Elevated #CK #differential
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Her clinical exam ... non-localized EOM ... weakness and bilateral ... cogan sign and the ice ... ophthalmology #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Postsynaptic: Myasthenia ... parainfluenza, Coxsackie, HIV ... , CMV, EBV - Bacterial ... Diagnosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Campylobacter jejuni - HIV ... , CMV, EBV - Influenza ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... neurological lesion: Clinical ... , HIV, CMV, HTLV ... Mycoplasma, Influenza, EBV ... disorders #diagnosis #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
immunodeficiency virus (HIV ... transplantation CLINICAL ... and cauda equina TREATMENT ... intensive care unit (ICU ... diagnosis #management #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... effect/Edema • EBV ... CNS #Infections #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
EMG: LMN Signs in ... conditions listed in differential ... diagnosis column Treatment ... motor neurons - IV ... Lateral #Sclerosis #neurology