7 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
start and stop dates ... non-essential drug/HDS treatments ... for alternative causes ... HBV, HCV, HEV, EBV ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... Treatment: • ... of emergency, ICU
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... CRITERIA FOR ICL ... EBV. CMV. ... #Lymphopenia #ICL ... #diagnosis #hematology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... infarction, Acute renal injury ... #differential #diagnosis
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential Diagnosis ... hypertension and/or drug treatment ... replacing the BM ... white blood cell aplasia ... #causes #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... - Lymphocyte rich ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology