16 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Treatment: • ... of emergency, ICU ... #management #treatment
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
and Treatment ... Phlebotomy - MH/CCF ... /CWRU EM Res @MetroHealth_EM ... #Differential #Diagnosis ... #Treatment #Management
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
COVID19 in the ICU ... data on mortality rate ... 31 • First US case ... #Management #Summary ... : Marino's The ICU
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... sepsis), PE, DAH, CHF ... Renal Failure Treatment ... organ dysfuxtion, ICU ... #management #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... start and stop dates ... non-essential drug/HDS treatments ... for alternative causes ... HBV, HCV, HEV, EBV
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... CRITERIA FOR ICL ... EBV. CMV. ... #Lymphopenia #ICL ... #diagnosis #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... - HIV, CMV, EBV ... Guillain-Barre Diagnosis ... Barre #Syndrome #diagnosis ... #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
include Crackles/Rales ... the determined cause ... #algorithm #management ... #heartfailure #chf ... #criticalcare #icu
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... bulbar muscles DIAGNOSIS ... and cauda equina TREATMENT ... intensive care unit (ICU ... #management #neurology