14 results
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... - Differential Diagnosis ... Vasculitis - Anti-GBM ... Disease - Double Positive ... (ANCA + anti-GBM
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Differential Diagnosis ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #differential #diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... antibody, Anti-GBM ... usually low in anti-GBM ... #management #treatment
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Richmond Agitation ... will vary with clinical ... Propofol infusion syndrome ... #CriticalCare #diagnosis ... #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... cirrhosis • Intra-pulmonary ... hepatopulmonary #syndrome ... #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... Aplastic Anemia Clinical ... Parvovirus B19 - EBV ... oncology #hematology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... biologics (CMV +++, EBV ... of emergency, ICU ... #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... Coxsackie, CMV, EBV ... hepatitis • Pulmonary ... #management #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- HIV, CMV, EBV ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... from a seated position ... Atorvastatin Diagnosis ... /I • SAMS clinical ... #management #treatment