26 results
Multiple Uses for Tranexamic Acid (TXA) - Evidence Based Indications and Dosing

Trauma < 3 hrs •
Multiple Uses for ... Thinking MTP YES ICH ... Indications #management #EBM
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Glomerular Proteinuria (Positive ... sediment - WBC/RBC casts ... proliferative • Anti-GBM ... Diagnosis #Algorithm #Causes
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... exclude false positives ... nephropathy • Thin GBM ... ) • Anti-GBM ... Diagnosis #Algorithm #Causes
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
- NEJM 1999 - ICU ... unnecessary and cause ... /vmoitra) #EBM
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... Subacute to Chronic Causes
Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in
Recruitment and Titrated Positive ... increased 28-day all-cause ... Recruitment #PEEP #ARDS #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... 100 mg/m2) : in case ... of emergency, ICU
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
: - ANCA-positive ... anti-ANCA ab, anti-GBM ... resolution chest CT
Decompression Sickness - The physical examination revealed diffuse violaceous skin mottling over his trunk and arms
extent of the nausea ... Clinical #Derm #EM ... #Pneumatosis #CT
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody, Anti-GBM ... usually low in anti-GBM ... Other tests: • CT ... Goodpasture's cause ... seen on chest CT