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diagnosis ebm rheumatology treatment visualabstract adultonset agglutinin anemia aspergillus betadglucan biomarkers cardiology cardiomyopathy classification cold comparison criticalcare echocardiogram effectiveness evidence
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
Targeted Temperature Management ... - A Randomized Clinical ... admitted to the ICU ... #CriticalCare #ICU ... VisualAbstract #EBM
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... - NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... Coxsackie, CMV, EBV ... #diagnosis #management ... #treatment #rheumatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) in hematologic ... cut-offs defined in clinical ... in HM • False positives ... colonization vs invasive disease ... - Frozen ice-pops
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Disease ... Viral Infection Clinical ... dehydrogenase • Positive ... - Mycoplasma, EBV ... hemolytic #anemia #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... number of sites of disease ... classification #hematology ... #oncology #management
Septal Hypertrophic Cardiomyopathy (HOCM) 52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) EM resident
Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... Cardiomyopathy #HOCM #HCM #clinical
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 Sepsis - Interventions that do / do not improve outcomes Do: - Have high index of suspicion and
others - infectious disease ... nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM
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