8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... Coxsackie, CMV, EBV ... #diagnosis #management ... #treatment #rheumatology
Septal Hypertrophic Cardiomyopathy (HOCM)

52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) 
EM resident
Septal Hypertrophic Cardiomyopathy ... Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... #HOCM #HCM #clinical
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Valvular heart disease ... Congenital heart disease ... Avoid ARBs • ICD ... support for patients clinically ... #cardiology #treatment
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #oncology #management
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
others - infectious disease ... nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Infections (e.g., EBV ... ▪ Autoimmune diseases ... Clinical Presentation ... #Hematology #HemeOnc
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
comprising langerin-positive ... populations) CLINICAL ... Birbeck granules (EM ... TREATMENT OPTIONS ... Histiocytosis #Diagnosis #Management