10 results
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
Targeted Temperature Management ... - A Randomized Clinical ... admitted to the ICU ... #CriticalCare #ICU ... VisualAbstract #EBM
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... - NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Septal Hypertrophic Cardiomyopathy (HOCM)

52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) 
EM resident
Septal Hypertrophic Cardiomyopathy ... Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... #HOCM #HCM #clinical
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Coxsackie, CMV, EBV ... Disease #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... Aplastic Anemia Clinical ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- HIV, CMV, EBV ... Guillain-Barre Clinical ... tachycardia, reversible cardiomyopathy ... Syndrome #diagnosis #management ... #treatment #neurology
Management of Marine Envenomations
 • North American Cnidaria - Hot water, Supportive care
 • Irukandji jellyfish
Management of Marine ... 6% acetic acid, ice ... 6% acetic acid, ice ... antibiotics EB ... #treatment #toxicology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Sepsis - Interventions that do / do not improve outcomes
Do:
- Have high index of suspicion and
nurses well, pay ICU ... Enroll patient in a clinical ... Interventions #Management ... Factors #Matter #EBM