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diagnosis management agglutinin anemia aspergillus betadglucan biomarkers cardiology cardiomyopathy causes cd4 ck classification cold comparison creatine disease ebm echocardiogram elevated
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... - NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... - Seizures: Trauma ... immobility • Critical ... Illness Myopathy (ICU ... #Elevated #CK #differential
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) in hematologic ... cut-offs defined in clinical ... in HM • False positives ... BAL GM does not differentiate ... - Frozen ice-pops
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
CD4 Lymphopenia (ICL ... DIAGNOSTIC CRITERIA FOR ICL ... EBV. CMV. ... #diagnosis #hematology ... #Differential #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... dehydrogenase • Positive ... - Mycoplasma, EBV ... younger pts) Differential ... hemolytic #anemia #hematology
Septal Hypertrophic Cardiomyopathy (HOCM) 52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) EM resident
Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... Cardiomyopathy #HOCM #HCM #clinical
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 Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... and usually CD15 positive ... classification #hematology
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