12 results
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
- A Randomized Clinical ... admitted to the ICU ... #TTM48 #TTH48 #CriticalCare ... #ICU #VisualAbstract ... #EBM
POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients
POLAR Randomized Clinical ... Hypothermia on Neurologic ... Hypothermia #TBI #CriticalCare ... #ICU #VisualAbstract ... #EBM
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Richmond Agitation ... will vary with clinical ... it should not cause ... #CriticalCare # ... diagnosis #management
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... - NEJM 1999 - ICU ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
organ dysfunction caused ... Clinical construct ... likelihood of prolonged ICU ... #QSOFA #SIRS #criticalcare ... #icu
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... (COVID19, CMV/EBV ... immobility • Critical ... Illness Myopathy (ICU ... #differential #diagnosis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... Lymphocytopenia DIAGNOSTIC ... EBV. CMV. ... #diagnosis #hematology ... #Differential #Causes
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... pregnancy, or other causes ... Clinical Significance ... #cullensign #em ... peritonitis #IM #FM #ICU
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
virus • CMV • EBV ... • Common clinical ... • Gram stain: Positive ... 90% • Culture: Positive ... #neurology #meningitis