28 results
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
vs 24 Hours and Neurologic ... - A Randomized Clinical ... admitted to the ICU ... #CriticalCare #ICU ... VisualAbstract #EBM
POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients
POLAR Randomized Clinical ... Hypothermia on Neurologic ... did not improve neurologic ... #CriticalCare #ICU ... VisualAbstract #EBM
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... - NEJM 1999 - ICU ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Family engagement Critical ... Richmond Agitation ... will vary with clinical ... #CriticalCare #diagnosis ... #management
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Sepsis - Diagnosis ... Clinical construct ... was defined as positive ... likelihood of prolonged ICU ... #criticalcare #icu
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... biologics (CMV +++, EBV ... of emergency, ICU ... #management #treatment
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Factors: • SICU ... > MICU, ♀, ↑Age ... : • Clinical Suspicion ... non-heparin A/C if clinical ... #Hematology #HemeOnc
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... immobility • Critical ... Illness Myopathy (ICU ... #differential #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... Coxsackie, CMV, EBV ... #management #treatment ... #rheumatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) in hematologic ... cut-offs defined in clinical ... in HM • False positives ... - Frozen ice-pops ... Galactomannan #diagnosis