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differential management syndrome algorithm barre causes cns guillain myasthenia treatment weakness aids cord disorders encephalitis eyelid gbs generalized guillainbarre hemophagocytic
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Her clinical exam ... non-localized EOM ... cogan sign and the ice ... #PhysicalExam #clinical ... ophthalmology #neurology
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 Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... of emergency, ICU
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
- Differential Diagnosis ... : Influenza, EBV ... Rhabdomyolysis, Critical ... #Differential #Diagnosis ... #causes #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
myasthenia Diagnosis ... Bedside: ice pack ... precipitated by: Drugs, infection ... #diagnosis #management ... #neurology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM ... HSP • Post-infectious ... #Proteinuria #Nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : - ANCA-positive ... allopurinol), Infection ... anti-ANCA ab, anti-GBM ... #nephrology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... Postsynaptic: Myasthenia Gravis ... Coxsackie, HIV, CMV, EBV ... #Differential #Diagnosis ... #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
- Differential Diagnosis ... should be based on clinical ... effect/Edema • EBV ... and <25% culture positive ... InfectiousDiseases #Neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... • Common clinical ... • Gram stain: Positive ... #neurology #meningitis
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
to a preceding infection ... transplantation CLINICAL ... specific therapy, the clinician ... intensive care unit (ICU ... #management #neurology
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