9 results
TTH48 - Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac
vs 24 Hours and Neurologic ... admitted to the ICU ... #TTM48 #TTH48 #CriticalCare ... #ICU #VisualAbstract ... #EBM
POLAR Randomized Clinical Trial - Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients
Hypothermia on Neurologic ... did not improve neurologic ... Hypothermia #TBI #CriticalCare ... #ICU #VisualAbstract ... #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... of emergency, ICU ... Lymphohistiocytosis #diagnosis
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Sepsis - Diagnosis ... host response to infection ... likelihood of prolonged ICU ... #QSOFA #SIRS #criticalcare ... #icu
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM ... HSP • Post-infectious ... #Proteinuria #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : - ANCA-positive ... allopurinol), Infection ... anti-ANCA ab, anti-GBM ... #nephrology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
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- Differential Diagnosis ... cells per μL • Diagnosis ... effect/Edema • EBV ... and <25% culture positive ... #differential #diagnosis
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... • Gram stain: Positive ... 90% • Culture: Positive ... #neurology #meningitis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
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CD4 Lymphopenia (ICL ... Lymphocytopenia DIAGNOSTIC ... myelodysplasia) • Infections ... EBV. CMV. ... #diagnosis #hematology