12 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Diagnosis for Pulmonary ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #diagnosis #nephrology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Coxsackie, CMV, EBV ... hepatitis • Pulmonary ... #management #treatment
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody, Anti-GBM ... usually low in anti-GBM ... Renal #Syndromes #differential ... #diagnosis #management ... #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... organ dysfuxtion, ICU ... #management #hematology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
infections (HPV, EBV ... Renal #Transplant #differential ... #diagnosis #kidney ... #blood #urine #management ... #treatment #nephrology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... myasthenia Diagnosis ... : - Bedside: ice ... Myasthenia #Gravis #diagnosis ... #management #neurology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... & Dry) is the treatment ... #diagnosis #differential ... #algorithm #management ... #criticalcare #icu
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... Antimicrobial treatment ... effect/Edema • EBV ... and <25% culture positive ... CNS #Infections #differential
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... cardiomyopathy • Pulmonary ... Avoid ARBs • ICD ... Cardiomyopathy #diagnosis ... #treatment