21 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Diagnosis for Pulmonary ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #differential # ... diagnosis #nephrology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - MH/CCF/CWRU EM ... #Causes #Differential ... #Diagnosis #Treatment ... #Management
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
Guillain-Barre Syndrome ... suspect 2️⃣ How to Diagnose ... When to admit to ICU ... 5️⃣ Treatment ... #Management #Neurology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... Diagnosis Algorithm ... • Fanconi's syndrome ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
infections (HPV, EBV ... (Goodpasture's syndrome ... #diagnosis #kidney ... #blood #urine #management ... #treatment #nephrology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Unknown cause Treatment ... of emergency, ICU ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... organ dysfuxtion, ICU ... #management #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... myasthenia Diagnosis ... : - Bedside: ice ... Myasthenia #Gravis #diagnosis ... #management #neurology
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Viruses (HSV, EBV ... Miller-Fisher GBS; Positive ... Rhombencephalitis #Differential ... #Diagnosis #Causes ... #Neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Diagnosis Framework ... and Management ... Myoglobinuria: UA positive ... #Diagnosis #Management ... #nephrology