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differential causes nephrology acute aki algorithm injury kidney rheumatology agglutinin anemia cold creatine disease elevated hemolytic hemophagocytic hlh icl idiopathic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... ANCA, ANA, Anti-GBM ... Anti-ds-DNA, C3/C4 ... Rhabdo-myolysis: CK ... , CK-MB, NT-proBNP
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Levels Acute CK ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... infarction, Acute renal ... #differential #diagnosis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
DIAGNOSTIC ... CRITERIA FOR ICL ... chemotherapy) • Genetic syndromes ... EBV. CMV. ... #diagnosis #hematology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... ab, ANA, C3, C4 ... #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
- Differential Diagnosis ... Abdominal Compartment Syndrome ... GN: ANCA, Anti-GBM ... , C3/C4, Other ... #nephrology #causes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... treatment #summary #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... dehydrogenase • Positive ... hemolysis • C3↓ C4 ... - Mycoplasma, EBV ... hemolytic #anemia #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... affects the skin, neurologic ... pain and GN Anti-GBM ... #Rheumatology
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