29 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU ... #management #treatment
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... Investigations: full blood ... ANCA, ANA, Anti-GBM ... screen, including blood ... • Cardio-renal syndrome
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
infections (HPV, EBV ... (Goodpasture's syndrome ... #differential #diagnosis ... #kidney #blood ... urine #management #treatment
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
and Mg2+ whose positive ... reduces renal blood ... reduced renal blood ... criticalcare #management #diagnosis ... #treatment #pharmacology
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
Guillain-Barre Syndrome ... suspect 2️⃣ How to Diagnose ... When to admit to ICU ... 5️⃣ Treatment ... #Management #Neurology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Fanconi's syndrome ... Glomerular Proteinuria (Positive ... proliferative • Anti-GBM ... #Proteinuria #Nephrology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Significance (ICUS ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... Parvovirus B19 - EBV ... aplastic anemia Treatment ... result from low blood ... oncology #hematology #diagnosis
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Viruses (HSV, EBV ... - Bickerstaff syndrome ... Miller-Fisher GBS; Positive ... #Differential #Diagnosis ... #Causes #Neurology