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diagnosis pathology clinical electronmicroscopy membranous differential renal classification comparison diseases glomerular glomerulus membranoproliferative microscopy mpgn pulmonary rpgn stage2 stage3 stage4
Stage III Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM from a biopsy with membranous
acellular scanning EM ... more extensive GBM ... surface of reticular GBM ... #MGN #stage3 #GBM ... #clinical #nephrology
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 Stage II Membranous Glomerulonephritis on Electron Microscopy This eyeSCANdy image shows acellular scanning EM of a glomerulus
acellular scanning EM ... appearance of GBM ... #MGN #stage2 #GBM ... ElectronMicroscopy #SEM ... #clinical #nephrology
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 Stage IV Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM of glomerular capillary loops from
acellular scanning EM ... completely bridged GBM ... #glomerulus #MGN ... ElectronMicroscopy #SEM ... #clinical #nephrology
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 Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
post-infectious GN ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Differential #Diagnosis #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... GN • Active Urine ... immune deposits on EM ... Membranoproliferative #Glomerulonephritis ... #MPGN #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Electron Microscopy (EM ... Post-infectious GN ... • Membranous GN ... RPGN • Anti-GBM ... glomerular #diseases #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... : - ANCA-positive ... anti-ANCA ab, anti-GBM ... resolution chest CT ... differential #diagnosis #nephrology
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